Human brain in neuroscience research and CNS drug discovery
  • Dragunow M. Human brain neuropharmacology: A platform for translational neuroscience. Trends Pharmacol Sci. 2020;41(11):777-792. This manuscript details the use of human brain tissue microarray, human brain cell culture, and high content screening in drug discovery and development for brain disorders.
  • Rustenhoven J, Jansson D, Smyth LC, Dragunow M. Brain Pericytes as Mediators of Neuroinflammation. Trends Pharmacol Sci. 2017;38(3):291-304.
  • Smith AM, Dragunow M. The human side of microglia. Trends Neurosci. 2014;37(3):125-135.
  • Dragunow M. Cell and tissue culture. In Aminoff MJ and Daroff RB (eds.) Encyclopedia of Neurological Sciences 2nd edition, Oxford: Academic Press 2014; 1:630-633.
  • Gibbons HM, Dragunow M. Adult human brain cell culture for neuroscience research. Int J Biochem Cell Biol. 2010;42(6):844-856.
  • Dragunow M. High-content analysis in neuroscience. Nat Rev Neurosci. 2008;9(10):779-88. This manuscript describes the high content analysis/screening techniques utilized by Neurovalida scientists for acquiring and analysing tissue microarray and human brain cell culture data.
  • Dragunow M. The adult human brain in preclinical drug development. Nat Rev Drug Discov. 2008;7(8):659-666. This manuscript provides the blueprint/theoretical basis for establishing NeuroValida and details the use of human brain tissue microarray and human brain cell culture in pre-clinical CNS drug development.
  • Waldvogel HJ, Bullock JY, Synek BJ, Curtis MA, van Roon-Mom WM, Faull RL. The collection and processing of human brain tissue for research. Cell Tissue Bank. 2008;9(3):169-179. This article details the protocols used at the Human Brain Bank for tissue processing.
  • Curtis MA, Faull RL, Eriksson PS. The effect of neurodegenerative diseases on the subventricular zone. Nat Rev Neurosci. 2007;8(9):712-23.
  • Waldvogel HJ, Curtis MA, Baer K, Rees MI, Faull RL. Immunohistochemical staining of post-mortem adult human brain sections. Nat Protoc. 2006;1(6):2719-2732. This article details the protocols used at the Human Brain Bank for tissue processing.
  • Bhardwaj RD, Curtis MA, Spalding KL, Buchholz BA, Fink D, Björk-Eriksson T, Nordborg C, Druid H, Eriksson PS, Frisen J. The age of human cerebral cortex neurons. Proc Natl Acad Sci U S A. 2006; 103:12564-12568.