Neuropharmacology/Neurochemistry
  • Young D, Fong DM, Lawlor PA, Wu A, Mouravlev A, McRae M, Glass M, Dragunow M, During MJ. Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy. Gene Ther. 2014;21(12):1029-40.
  • Graham ES, Woo KK, Aalderink M, Fry S, Greenwood JM, Glass M, Dragunow M. M1 muscarinic receptor activation mediates cell death in M1-HEK293 cells. PLoS One. 2013;8(9):e72011.
  • Heapy A, Dragunow M, Brimble M. Synthesis of the cysteine protease inhibitors CPI-2081a and CPI-2081b using a controlled SPPS by-product forming reaction. Synlett 2013; 24(14): 1818-1824.
  • Dragunow M. Meningeal and choroid plexus cells--novel drug targets for CNS disorders. Brain Res. 2013;1501:32-55.
  • Coppieters N, Dragunow M. Epigenetics in Alzheimer's disease: a focus on DNA modifications. Curr Pharm Des. 2011;17(31):3398-412.
  • Narayan P, Dragunow M. Pharmacology of epigenetics in brain disorders. Br J Pharmacol. 2010;159(2):285-303.
  • Dragunow M. Purinergic Mechanisms in Epilepsy. Open Neurosci J., 2010, 4: 31-34.
  • Greenwood JM, Dragunow M. M3 muscarinic receptors promote cell survival through activation of the extracellular regulated kinase (ERK1/2) pathway. Eur J Pharmacol. 2010;640(1-3):38-45.
  • Dragunow M. M3 muscarinic receptors as targets for drug development in neurodegenerative disorders. Nat Rev Drug Discov. 2008;7(2):1 p following p185.
  • Zhang S, Liu J, Dragunow M, Cooper GJ. Fibrillogenic amylin evokes islet beta-cell apoptosis through linked activation of a caspase cascade and JNK1. J Biol Chem. 2003;278(52):52810-9.
  • Greenwood JM, Dragunow M. Muscarinic receptor-mediated phosphorylation of cyclic AMP response element binding protein in human neuroblastoma cells. J Neurochem. 2002;82(2):389-97.
  • Abraham WC, Logan B, Greenwood JM, Dragunow M. Induction and experience-dependent consolidation of stable long-term potentiation lasting months in the hippocampus. J Neurosci. 2002;22(21):9626-34.
  • Zhang S, Liu J, MacGibbon G, Dragunow M, Cooper GJ. Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells. J Mol Biol. 2002;324(2):271-85.
  • Walton MR, Dragunow I. Is CREB a key to neuronal survival? Trends Neurosci. 2000;23(2):48-53.
  • Young D, Lawlor PA, Leone P, Dragunow M, During MJ. Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nat Med. 1999;5(4):448-53.
  • Walton M, Connor B, Lawlor P, Young D, Sirimanne E, Gluckman P, Cole G, Dragunow M. Neuronal death and survival in two models of hypoxic-ischemic brain damage. Brain Res Brain Res Rev. 1999;29(2-3):137-68.
  • Connor B, Dragunow M. The role of neuronal growth factors in neurodegenerative disorders of the human brain. Brain Res Brain Res Rev. 1998;27(1):1-39.
  • Dragunow M, MacGibbon GA, Lawlor P, Butterworth N, Connor B, Henderson C, Walton M, Woodgate A, Hughes P, Faull RL. Apoptosis, neurotrophic factors and neurodegeneration. Rev Neurosci. 1997;8(3-4):223-65.
  • Hughes P, Dragunow M. Induction of immediate-early genes and the control of neurotransmitter-regulated gene expression within the nervous system. Pharmacol Rev. 1995;47(1):133-78.
  • Dragunow M, Preston K. The role of inducible transcription factors in apoptotic nerve cell death. Brain Res Brain Res Rev. 1995;21(1):1-28.
  • Glass M, Dragunow M. Neurochemical and morphological changes associated with human epilepsy. Brain Res Brain Res Rev. 1995;21(1):29-41.
  • MacGibbon GA, Lawlor PA, Bravo R, Dragunow M. Clozapine and haloperidol produce a differential pattern of immediate early gene expression in rat caudate-putamen, nucleus accumbens, lateral septum and islands of Calleja. Brain Res Mol Brain Res. 1994;23(1-2):21-32.
  • Abraham WC, Christie BR, Logan B, Lawlor P, Dragunow M. Immediate early gene expression associated with the persistence of heterosynaptic long-term depression in the hippocampus. Proc Natl Acad Sci U S A. 1994;91(21):10049-53.
  • Dragunow M. Adenosine and seizure termination. Ann Neurol. 1991;29(5):575.
  • Dragunow M, Robertson GS, Faull RL, Robertson HA, Jansen K. D2 dopamine receptor antagonists induce fos and related proteins in rat striatal neurons. Neuroscience. 1990;37(2):287-94.
  • Dragunow M. GABA and seizure initiation in vivo. Trends Neurosci. 1989;12(1):10-11.
  • Dragunow M. Possible complications of pentoxifylline in stroke. Stroke. 1989;20(8):1115-6.
  • Dragunow M, Faull R. The use of c-fos as a metabolic marker in neuronal pathway tracing. J Neurosci Methods. 1989;29(3):261-5.
  • Dragunow M, Robertson HA. Seizure-inducible c-fos protein(s) in mammalian neurons. Trends Pharmacol Sci. 1988;9(1):5-6.
  • Dragunow M, Faull RL. Neuroprotective effects of adenosine. Trends Pharmacol Sci. 1988;9(6):193-194.
  • Dragunow M, Robertson HA. Kindling stimulation induces c-fos protein(s) in granule cells of the rat dentate gyrus. Nature. 1987;329(6138):441-442.
  • Dragunow, M. Adenosine: The Brain's Natural Anticonvulsant? Trends Pharmacol Sci. 1986;7(4), 128‑130.